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Despite being extremely shy, she blooms on stage and loves to sing. Pelphrey is discovering that girls with autism are indeed different from other girls in how their brain analyzes social information. Instead their pastimes and preferences are more similar to those of other girls. Their mom, Page, can recall how different the diagnostic process was for her two children. She could make herself a dead weight and just—you couldn't pick her up.
Notably, females with autism may be closer to typically developing males in their social abilities than typical girls or boys with autism. Pelphrey is finding that autism also highlights normal developmental differences between girls and boys. This article was originally published with the title "The Invisible Girls". Typical girls who get school credit for volunteering provide mentoring and talk about boys and other issues the girls might not want to discuss with adults. Girls in the study will be compared with autistic boys, as well as typically developing children of both sexes, using brain scans, genetic testing and other measures. Despite being extremely shy, she blooms on stage and loves to sing. And then, she copied them—learning what most folks absorb naturally on the playground only through voracious novel reading and the aftermath of embarrassing gaffes. Even many highly intelligent girls on the spectrum have difficulties with washing their hair, wearing deodorant and dressing appropriately, Jamison says. Yet autistic girls tend to show a much greater desire to connect. Further, because autism and ADHD often occur together—and because people diagnosed with ADHD tend to have higher levels of autism traits than typical people do—girls who seem easily distracted or hyperactive may get this label, even when autism is more appropriate. In he and his colleagues found that male fetuses exposed to higher levels of testosterone in amniotic fluid during pregnancy tend to grow up to have more autism traits. In Baron-Cohen and his colleagues published results of an analysis of a large group of amniotic fluid samples from Denmark that are linked to population registries of mental health. A second idea emerges when looking at the typical strengths of women. Some research hints at the connection between anorexia and autism: McGillivray and her colleagues compared 25 autistic boys and 25 autistic girls with a similar number of typically developing children. A study published in by Baron-Cohen and his colleagues found that 66 percent of adults with the milder form of ASD so-called Asperger's reported suicidal thoughts, a rate nearly 10 times higher than that seen in the general population. And although she is laconic and does not tend to initiate conversation, she is also bubbly and smiles frequently, clearly interested in connecting. She could make herself a dead weight and just—you couldn't pick her up. They, too, found that girls with the diagnosis were more likely to have low IQs and extreme behavior problems. O'Toole's behavior might have seemed like typical make-believe to her parents because she staged Barbie weddings just like other little girls. Already Pelphrey is seeing fascinating differences in autistic girls in his preliminary research. Along these lines, several studies have shown that in families with affected daughters, there are higher numbers of mutations known as copy-number variations than there are in families where only boys are affected. This finding suggests that clinicians are missing many girls who are on the less disabling end of the autism spectrum, previously designated Asperger's syndrome. On a measure of friendship quality and empathy, autistic girls scored as high as typically developing boys the same age—but lower than typically developing girls. The proportion was 71 percent among women, who made up about one third of the sample.
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